I-collagen, uhlobo lweprotheyini yesakhiwo kwi-matrix engaphandle, ibizwa ngokuba yiCollagen, eyavela kwisiGrike.I-Collagen yiprotheni emhlophe, e-opaque kunye ne-unbranched fibrous efumaneka kwi-skin, ithambo, i-cartilage, amazinyo, i-tendon, i-ligaments kunye nemithambo yegazi yezilwanyana.Yiprotheni ebaluleke kakhulu yesakhiwo sezicubu ezidibeneyo, kwaye idlala indima ekuxhaseni amalungu kunye nokukhusela umzimba.I-Collagen yeyona proteni ininzi kwizilwanyana ezincancisayo, ibalwa kwi-25% ukuya kwi-30% yeprotheyini epheleleyo emzimbeni, ilingana ne-6% yobunzima bomzimba.
Kwiminyaka yakutshanje, ngophuhliso lwetekhnoloji yokutsalwa kwe-collagen kunye nezifundo ezinzulu malunga nesakhiwo kunye neempawu zayo, imisebenzi yebhayoloji ye-collagen hydrolysates kunye ne-polypeptides ngokuthe ngcembe iye yaqatshelwa ngokubanzi.Uphando kunye nokusetyenziswa kwe-collagen kuye kwaba yindawo yophando kwizonyango, ukutya, izimonyo kunye namanye amashishini.
Ukongeza kwi-tryptophan kunye ne-cysteine, i-collagen iqulethe i-amino acids eyi-18, i-7 ebalulekileyo ekukhuleni komntu.I-glycine kwi-collagen i-akhawunti ye-30%, kwaye i-proline kunye ne-hydroxyproline kunye ne-akhawunti malunga ne-25%, eyona iphakamileyo phakathi kwazo zonke iintlobo zeeprotheni.Umxholo we-alanine kunye ne-glutamic acid nawo uphezulu kakhulu.Ukongeza, ikwaqulethe i-hydroxyproline kunye ne-pyroglutamic acid, engafane ibonwe kwiiprotheni eziqhelekileyo, kunye ne-hydroxyllysine, ephantse ingabikho kwezinye iiprotheni.
I-Collagen yiprotheni yesakhiwo kwi-matrix ye-extracellular apho iimolekyuli zayo zidityaniswe kwizakhiwo ze-supramolecular.Ubunzima bemolekyuli yi-300 ku.Olona phawu luqhelekileyo lwesakhiwo se-collagen sisakhiwo se-helix kathathu, equlathe iipolypeptides ezintathu zealpha kumxokelelwane we-alpha osekhohlo, nganye kuwo ijijelwe ukwenza isakhelo se-alpha helix sasekunene.
Ulwakhiwo olukhethekileyo lwe-helix kathathu lwe-collagen lwenza ukuba ulwakhiwo lwalo lwe-molecular luzinze kakhulu, kwaye lune-immunogenicity ephantsi kunye ne-biocompatibility efanelekileyo.Isakhiwo simisela ipropati, kwaye ipropati imisela ukusetyenziswa.Ukwahluka kunye nobunzima besakhiwo se-collagen sinquma isikhundla saso esibalulekileyo kwiinkalo ezininzi, kunye neemveliso ze-collagen zinethuba elihle lokufaka isicelo.
I-Collagen yintsapho yeeprotheni.Ubuncinci ngama-30 eejeni ezikhowudiweyo zamatyathanga e-collagen afunyenweyo, anokwenza ngaphezulu kwe-16 iintlobo zeemolekyuli ze-collagen.Ngokuhambelana nokusabalalisa kwabo kunye neempawu zokusebenza kwi-vivo, i-collagen okwangoku yahlulahlulwe kwi-collagen ye-interstitial, i-basal membrane collagen kunye ne-pericellular collagen.Iimolekyuli ze-collagen ze-Interstitial zibandakanya uninzi lwe-collagen kumzimba wonke, kubandakanywa uhlobo Ⅰ, Ⅱ kunye ne-Ⅲ i-collagen molekyuli, ezisasazwa kakhulu eluswini, i-tendon kunye nezinye izicubu, phakathi kwazo uhlobo lwe-Ⅱ collagen oluveliswa yi-chondrocytes.I-basement membrane collagen idla ngokubizwa ngokuba luhlobo Ⅳ collagen, esasazwa ikakhulu kwinwebu engaphantsi.I-Pericellular collagen, ngokuqhelekileyo ibhala i-Ⅴ collagen, ikhona ngobuninzi kwizicubu ezidibeneyo.
Ukupakishwa kwethu yi-25KG uhlobo lwe-collagen olufakwe kwisikhwama se-PE, emva koko isikhwama se-PE sifakwe kwidramu yefiber kunye nelokhi.Imigqomo engama-27 ifakwe kwipalethi enye, kwaye enye i-20 yeenyawo isikhongozeli iyakwazi ukulayisha malunga nama-800 amagubu angama-8000KG ukuba ipalleted kunye ne-10000KGS ukuba ayifakwanga.
Iisampuli zasimahla ezijikeleze i-100 grams ziyafumaneka kuvavanyo lwakho xa uceliwe.Nceda uqhagamshelane nathi ukuze ucele isampuli okanye ikowuti.
Sineqela lokuthengisa leengcali elibonelela ngokukhawuleza nangempendulo echanekileyo kwimibuzo yakho.Siyathembisa ukuba uya kufumana impendulo kumbuzo wakho kwiiyure ezingama-24.
Ixesha lokuposa: Dec-05-2022